Thursday, 29 May 2008

BART study published

The BART study has been published in today's NEJM. 

The BART study randomised cardiac surgery patients to receive either aprotinin, tranexaminc acid or aminocaproic acid.
The finding were a modest benefit for aprotinin for reduction in bleeding, but a higher 30 day mortality. This RCT follows on from an earlier Mangano study which found worse outcome from the use of aprotinin to reduce bleeding in cardiac surgery.

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