Wednesday, 13 October 2010

The last round for codeine?

Codeine has been an historically popular drug. This has been particularly due to its availability in many over-the-counter combination analgesic drugs such as Panadeine and cold-and-flu remedies. The problem is that codeine is a pro-drug for morphine which depends on the highly variable pharmacokinetics of individual patients. This editorial from the CMJ argues that it is better and safer for patients to avoid codeine and just use a predictable opioid such as morphine or oxycodone.

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