Thursday, 17 March 2011

Prevention of Pain on injection from Propofol

This meta-analysis assessed various methods to prevent pain on injection from propofol. This totalled 170 studies and 25,000 adult patients. The most effective methods were using the ante-cubital vein (RR 0.14) and injection of lignocaine combined with venous occlusion (RR 0.29). Interestingly the new MCT/LCT formulation were not very effective with a relative risk reduction of only 0.75. The article also scored an editorial. And it's in a general medical journal too.