Thursday, 1 May 2014

Aspirin in patients Undergoing Non-cardiac Surgery. NEJM March 2014.

What is the best management of peri-operative aspirin? This international randomised, controlled trial looked at the value of peri-operative aspirin in patients at risk of vascular complication undergoing non-cardiac surgery. Neither the rate of death nor nonfatal myocardial infarction was affected by the use of peri-operative aspirin. There was an increased risk of major bleeding in the aspirin group. In fact, major bleeding was an independent predictor of myocardial infarction. Patients who had received a bare-metal stent (less than 6 weeks) or a drug-eluting stent (less than 1 year) before surgery were excluded.

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