Monday, 14 March 2016

Is ketamine ready to be used clinically for the treatment of depression? MJA Dec 2015.

To date, 8 randomised placebo-controlled trials involving almost 200 participants with depression showed antidepressant effects after a single dose of ketamine of 0.5mg/kg over 40 minutes IV.  A major drawback is that the antidepressant effects typically last for only several days after a single treatment. Recently Australian health authorities have curtailed medical practitioners offering a course of ketamine treatments to patients with depression. http://www.abc.net.au/news/2015-05-30/ketamine-offered-to-patients-with-depression-in-take-home-packs/6508232 A new trial is underway to assess the effects of a four week course of ketamine on patients with depression who have not responded to existing medications. http://www.abc.net.au/news/2015-11-09/grant-of-$2m-awarded-for-ketamine-depression-treatment-trial/6923788

Let’s watch this space.

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